The exclusion of protein by hyaluronic acid. Measurement by light scattering.
نویسندگان
چکیده
Light scattering measurements have been made on solutions of hyaluronic acid in the presence and absence of bovine serum albumin. The results are interpreted as showing an exclusion of bovine serum albumin from molecules of hyaluranic acid, the magnitude of which agrees with most other measurements of exclusion. The theory of the effect of heterogeneity of exclusion is given. The apparent heterogeneity that is observed is explained on statistical grounds. The results suggest that the main cause of exclusion is steric. No significant effect of bovine serum albumin on the configuration of the hyaluronic acid was observed.
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 241 1 شماره
صفحات -
تاریخ انتشار 1966